I found a press release from JDRF related to MANF this morning. As I mentioned in my previous blogs, MANF is an attractive target for Wolfram syndrome and type 1 diabetes. In addition to protecting insulin-producing cells from ER stress-mediated cell death, I think that MANF could protect brain cells and eye cells from death. We will keep on working on this molecule.
http://jdrf.org/blog/2014/specific-protein-may-help-beta-cells-survive-in-type-1-diabetes-2/
