Combating Wolfram Syndrome

Our current strategies for developing a treatment for Wolfram are the following. 1. Inactivate molecules that play important roles in ER...

We are looking for drugs that can prevent the progression of neuronal cell death in Wolfram syndrome utilizing different strategies. The cha...

The endoplasmic reticulum (ER) is a cellular organelle found in virtually every human cell. The ER participates in many important c...

Wolfram syndrome is a autosomal recessive disorder characterized by juvenile onset diabetes, later followed by various neurological dysfunct...

Here is the three step formula for developing a novel therapy for Wolfram syndrome.   1. Understand the disease 2. Identify drug targ...